Journal Article

Blind analysis: Hide results to seek the truth

More fields should, like particle physics, adopt blind analysis to thwart bias, urge Robert MacCoun and Saul Perlmutter.

Decades ago, physicists including Richard Feynman noticed something worrying. New estimates of basic physical constants were often closer to published values than would be expected given standard errors of measurement1. They realized that researchers were more likely to 'confirm' past results than refute them — results that did not conform to their expectation were more often systematically discarded or revised.

A fluoroscopy-based planning and guidance software tool for minimally invasive hip refixation by cement injection

In orthopaedics, minimally invasive injection of bone cement is an established technique. The authors present HipRFX, a software tool for planning and guiding a cement injection procedure for stabilizing a loosening hip prosthesis. HipRFX works by analysing a pre-operative CT and intraoperative C-arm fluoroscopic images.

The founding charter of the Genomic Observatories Network

The co-authors of this paper hereby state their intention to work together to launch the Genomic Observatories Network (GOs Network) for which this document will serve as its Founding Charter. We define a Genomic Observatory as an ecosystem and/or site subject to long-term scientific research, including (but not limited to) the sustained study of genomic biodiversity from single-celled microbes to multicellular organisms.