Journal Article

Multivariate GWAS: Generalized Linear Models, Prior Weights, and Double Sparsity


Background: Consecutive testing of single nucleotide polymorphisms (SNPs) is usually employed to identify genetic variants associated with complex traits. Ideally one should model all covariates in unison, but most existing analysis methods for genome-wide association studies (GWAS) perform only univariate regression.

SkyPortal: An Astronomical Data Platform

SkyPortal is a web application that stores and interactively displays astronomical datasets for annotation, analysis, and discovery. It is designed to be modular and extensible, so it can be customized for various scienti c use cases. It is released under the Modi ed BSD license.

SkyPortal was designed with time-series survey data from the Zwicky Transient Facility, and eventually The Large Synoptic Survey Telescope, in mind.