Abstract: Recent discoveries in multi-messenger astrophysics have opened up new windows of exploration to the universe. The detection of gravitational waves (GW) from a binary neutron star merger followed by a short gamma-ray burst recorded the first multi-messenger event involving GWs. In addition, the detection of a high-energy neutrino (HEN) followed by electromagnetic emissions from a flaring blazar was the first compelling evidence for HEN source association. However, no astrophysical source has yet been observed to generate both GWs and HENs. Multi-messenger searches for GWs and HENs provide important insights into the dynamics of and particle acceleration by black holes and neutron stars. The rapid identification of joint signals is crucial for electromagnetic follow-up observations of transient emission that is only detectable for short periods of time. I will present the latest sensitivity of realtime searches of HENs and GWs, and discuss the role of follow-up observations in identifying electromagnetic counterparts to joint GW+HEN events.